Multiple Sclerosis Overview 2024



00:52 MRI 2:59 Symptoms, relapses, progression 5:03 Types of MS 7:14 Central Vein 7:50 Misdiagnosis 9:04 Myelin 10:08 Spinal …

25 Comments

  1. There should be a cure by now.!Alot of research.!
    Too many years.!
    You can put man on moon? What! This is scary shit!
    Come on people.
    I know they have a cure.
    Big pharma is keeping people sick!
    Go Europe!

  2. (I am re-writing this question, after having watched your video published about a year ago on the difference between MS and vascular disease lesions appearing in an MRI).
    In the list of alternative diagnoses in MS misdiagnosis (around timestamp 8:54), which (if any) in that list would share the more nuanced features of MS lesions. Specifically, in addition to being located in the regions typical of MS brain lesions (periventricular and/or juxicortical), which of these diseases, if any, would also be commonly associated with a central vein sign, and/or have a Dawson Finger's morphology, and or persist on the MRI for several years and evolve into a "black hole" as seen on an MRI image?

  3. Excellent overview, Dr. Brandon. Thank you! Two related question for you: In the chart presented around the 6:30 timestamp (the plots of disability vs time), how would you categorize the following situations:
    (1) Suppose that there is a single but non-negligible "bump" at the far left side of the bottom plot (the plot for Primary Progressive MS). In other words, one distinct attack at very early time. Would that one bump, by definition, eliminate the primary progressive label?
    (2) Let's now talk about the slope of that line. How relevant is the slope to the category in which the diagnosis is placed? Suppose, for example, that the slope is significantly shallower than what is shown in that bottommost plot (Let's say that the line is definitely sloped, but just not nearly as steeply as shown). Still considered to be "primary progressive" ? Thanks!

  4. Thanks for the video Doc, Iโ€™ve had MS for 15 years, got it at 19, have an amazing doc who gave me the right meds at the right time, the first attack was bad, had double vision, lost taste, couldnโ€™t stand or walk. Had a couple of relapses since, on medication for RRMS now, Iโ€™m feeling much better, have trouble walking for more than 1km at a stretch though. ๐Ÿ˜Š

  5. I healed my MS after 15 years WITH MOLECULAR HYDROGEN ๐Ÿ’ง๐Ÿ’จ๐Ÿ’ฏ๐Ÿค” i knew there was a cureโค๐Ÿ˜Š โค if you're a serious neurologist you'd look I'm it. ๐Ÿ’ง๐Ÿ’จ๐Ÿ™๐Ÿพ

  6. Hi Dr. Beaber

    Excellent video! I learned more about my condition (RRMS). I have a question regarding OCB since you mentioned it on the video: I got on my spinal tap 6 OCB, but zero on the blood serum.

    What is the prognosis?

    Thank you and have a great weekend!

  7. My sister has MS. She seems to live on another planet. She thinks the normal rules of life that apply to people don't apply to her. She thinks she can walk on water and that money grows on trees. She is totally irresponsible with money.
    She had huge exposure to the sun growing up in Perth, Aus. So I question the sun theory.

  8. Very good overview of MS in 2024! My story:

    Dxd in 1993 at age 22 while serving in the USN. Relapsing/remitting with only a few relapses until 1998. Started my first DMT (Betaseron) that same year. Symptoms included increasing gait problems and MASSIVE fatigue. Stopped working in 2005. EDSS continued to worsen. Started ocrelizumab in 2018 when I hit EDSS of 6.5. I am currently still at 6.5, although memory, cognition, and processing seem to be worsening. MRIs show very significant atrophy with many lesions in brain that seem to be morphing into one another, also black holes. Lesions throughout cervical and thoracic spine. Upper body seems to be relatively ok, and I go to the gym to weight train at least 5x a week. Current age is 53. Trying to stay out of the chair.

  9. @23:12 I wish researchers would split this data based on demographics. Say only taking people diagnosed within a 10 year time window for instance rather than lumping everyone together. A 30 year old with MS may be far less likely than a 60 year old to need a cane 10 years later post diagnosis for example. It muddies the water in my opinion. The age chart at @24:10 is a good example of this ๐Ÿ™‚

  10. Fabulous video ๐Ÿ‘Œ thank you. I am 58 and was diagnosed with RRMS at 37. However, my first relapse, optic neaurits, occurred age 33. Disease onset was age 13 with spasms in my left leg, which continue to the present day. It is possible that I am transferring to SPMS and may therefore be prescribed Siponimod.

  11. Requesting an Opinion: I have had most physical symptoms of MS. However, my doctors (I'm a vet and my VA docs always changing) never review my MRIs for MS. One mentioned that my symptoms were synonymous with MS in passing once but never followed up.
    I was diagnosed with neuropathy and radiculopathy years ago and have chronic issues with recurring back and leg pain, stiffness, face, and neck tingling, even talking clearly at one time. But it comes and goes.
    I'm in my 40s, and this started in my 20s. Scheduled for surgery next month to relieve nerve pain.
    Should I be concerned about MS, or would it have been evident on my MRIs and addressed? Could some nerve pain be MS related? Thanks
    Blessings of good health to all!

  12. Mom diagnosed 1954-1967 RIPโ€ฆ@ 38 โ€ฆ.
    MS destroyed my mom along with our family โ€ฆ her treatment back then eat liver and take high doses of vitamin Cโ€ฆ uselessโ€ฆ๐Ÿ™๐Ÿผ

  13. Thanks for all your very informative videos, if not for mself ( 66 yr PMS EDSS 9 ) then for my daughter who has just been diagnosed with optic neuritis and ms. I have had my dx 33 yrs ago and have tried copaxone and rebif among others, but mostly I was too late and beyond repair. Now I just hope save as much of my cognetive functions as possible.Any suggestions on that would be welcome

  14. Hi Dr. Beaber, thank you very much for your videos. I am newly diagnosed with RRMS and my neurologist recommended ocrevus. I have my first infusion Feb. 19th and I am super nervous. I'm 42 yrs old whose only problem in the past has been hypertension. What brought me to the doctor was facial tingling on my right side constantly for the past 7 months even though I've had numerous of other symptoms head to toe. And since I'm so late getting diagnosed, I'll probably be stuck with this tingling for the rest of my life, I guess. ๐Ÿ˜’

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